SACS Antibody

Images

 
Western Blot: SACS Antibody [24340002] - Samples: Lane 1, Marker [kDa]: 250, 130, 95, 72, 55, 36, 28, 17, 11 Lane 2, RT-4 Lane 3, U-251MG sp Lane 4, Human Plasma Lane 5, Liver Lane 6, Tonsil, Target weight ...read more
ELISA: SACS Antibody [24340002]

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

SACS Antibody Summary

Immunogen
This antibody is specific for the C Terminus Region of the target protein.
Specificity
This product is specific for Human SACS.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SACS
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:5000-1:20000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
This antibody is useful in ELISA, Immunohistochemistry-Paraffin and Western Blot.
Publications
Read Publications using 24340002.

Reactivity Notes

Human.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Potassium Phosphate (pH 7.0) and 0.15M NaCl
Preservative
No Preservative
Purity
Immunogen affinity purified

Notes

Manufactured by SDIX's proprietary Genomic Antibody Technology™. GAT FAQs.

Alternate Names for SACS Antibody

  • ARSACS
  • dnaJ homolog subfamily C member 29
  • DNAJC29
  • KIAA0730
  • SACS
  • Sacsin
  • spastic ataxia of Charlevoix-Saguenay (sacsin)

Background

This gene consists of nine exons including a gigantic exon spanning more than 12.8k bp. It encodes the sacsin protein, which includes a UBQ region at the N-terminus, a HEPN domain at the C-terminus and a DnaJ region upstream of the HEPN domain. The gene is highly expressed in the central nervous system, also found in skin, skeletal muscles and at low levels in the pancreas. Mutations in this gene result in autosomal recessive spastic ataxia of Charlevoix-Saguenay (ARSACS), a neurodegenerative disorder characterized by early-onset cerebellar ataxia with spasticity and peripheral neuropathy. Alternatively spliced transcript variants encoding different isoforms have been found, but the full-length nature of these variants has not been determined.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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24340002
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
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Publications for SACS Antibody (24340002)(2)

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Array 24340002

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Bioinformatics

Gene Symbol SACS
Entrez
Uniprot