S1P5/EDG-8 Antibody

Western Blot: S1P5/EDG-8 Antibody [NBP3-12308] - (A) AND T47D cells (B). 1:500 antibody dilution in DiluObuffer. Apparent MW is 49 KDa.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

S1P5/EDG-8 Antibody Summary

• Description: Novus Biologicals Rabbit S1P5/EDG-8 Antibody (NBP3-12308) is a polyclonal antibody validated for use in WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Synthetic peptide taken within amino acid region 380-400 of rat S1P5R/EDG8 protein.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: S1PR5
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Western Blot 1:500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for S1P5/EDG-8 Antibody

• EDG8
• Edg-8
• EDG8S1P receptor Edg-8
• Endothelial differentiation G-protein-coupled receptor 8
• endothelial differentiation, sphingolipid G-protein-coupled receptor, 8
• LPB4
• S1P receptor 5
• S1P5
• S1PR5
• sphingosine 1-phosphate receptor 5
• sphingosine 1-phosphate receptor EDG8
• Sphingosine 1-phosphate receptor Edg-8
• sphingosine-1-phosphate receptor 5
• SPPR-1
• SPPR-2

Background

Edg8 is a Lysophospholipid/Lysosphingolipid Receptor activated by sphingosine-1-phosphate. Two differently expressed splice variants, 2.4 kb and 5.4 kb, are produced by alternative splicing. Edg8 has been reported in rat brain, lung, small intestine, spinal cord, and spleen. ESTs have been isolated from human cancer libraries of the head/neck and skin, as well as mouse brain and liver libraries. Caution: The rat EDG-8 gene has also been described as NRG-1, but should not be confused with the neuregulin-1 gene whose approved symbol is NRG-1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: S1PR5