S1P5/EDG-8 Products

Description

Edg8 is a Lysophospholipid/Lysosphingolipid Receptor activated by sphingosine-1-phosphate. Two differently expressed splice variants, 2.4 kb and 5.4 kb, are produced by alternative splicing. Edg8 has been reported in rat brain, lung, small intestine, spinal cord, and spleen. ESTs have been isolated from human cancer libraries of the head/neck and skin, as well as mouse brain and liver libraries. Caution: The rat EDG-8 gene has also been described as NRG-1, but should not be confused with the neuregulin-1 gene whose approved symbol is NRG-1.

Bioinformatics

Entrez	53637 Human
Uniprot	NM_030760 Human NP_001159687 Human NP_110387.1 Human Q9H228 Human
Product By Gene ID	53637
Alternate Names	Edg-8 EDG8S1P receptor Edg-8 Endothelial differentiation G-protein-coupled receptor 8 endothelial differentiation, sphingolipid G-protein-coupled receptor, 8 S1P receptor 5 S1P5 sphingosine 1-phosphate receptor 5 sphingosine 1-phosphate receptor EDG8 Sphingosine 1-phosphate receptor Edg-8 sphingosine-1-phosphate receptor 5 SPPR-1 SPPR-2

Research Areas for S1P5/EDG-8

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GPCR