Recombinant Human RXR alpha/NR2B1 Protein

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SDS-Page: Recombinant Human RXR alpha/NR2B1 Protein [NBC1-18416] - RXR-a, 13.6 kDa (119 aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human RXR alpha/NR2B1 Protein Summary

Description
An un-tagged recombinant protein corresponding to the amino acids111-228 of Human RXR alpha/NR2B1

Source: E.coli

Amino Acid Sequence: MLGLNGVLKV PAHPSGNMAS FTKHICAICG DRSSGKHYGV YSCEGCKGFF KRTVRKDLTY TCRDNKDCLI DKRQRNRCQY CRYQKCLAMG MKREAVQEER QRGKDRNENE VESTSSANE

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
RXRA
Purity
>95% pure by SDS-PAGE

Applications/Dilutions

Theoretical MW
13.6 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl pH7.5, 0.1M NaCl, 5mM beta-Mercaptoethanol
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>95% pure by SDS-PAGE

Alternate Names for Recombinant Human RXR alpha/NR2B1 Protein

  • FLJ00280
  • FLJ00318
  • FLJ16020
  • MGC102720
  • NR2B1
  • NR2B1FLJ16733
  • Nuclear receptor subfamily 2 group B member 1
  • retinoic acid receptor RXR-alpha
  • Retinoid X receptor alpha
  • retinoid X receptor, alpha
  • RXR alpha
  • RXRA

Background

The retinoid X receptor(RXR) is a pleiotropic nuclear receptor transcription factor that interacts with a variety of nuclear receptor dimeric partner. RXR binds cognate response elements as a homodimer in the presence of its ligand, 9-cis retinoic acid, or as a heterodimer with other members of the nuclear hormone receptor superfamily including retinoic acid receptors(RAR), thyroid hormone receptors(TR), vitamin D receptors and peroxisome proliferators-activated receptors(PPAR). The RXR family includes three difference isoforms ; RXR alpha, beta, gamma. Human RXR alpha gene is localized on 9q34.9 and encodes two major isoforms(RXR alpha1, RXR alpha2). The DNA binding domain of RXR(111-228aa) was over expressed in E.coli and purified by using conventional column chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol RXRA
Entrez