RUVBL2 Antibody (OTI2B9) [CoraFluor™ 1]

• Reactivity: Hu, Mu, Rt, Ca, Pm
• Applications: WB, Flow, CyTOF-ready
• Clone: OTI2B9
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: CoraFluor 1

RUVBL2 Antibody (OTI2B9) [CoraFluor™ 1] Summary

• Description: CoraFluor(TM) 1 is a high performance terbium-based TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) or TRF (Time-Resolved Fluorescence) donor for high throughput assay development. CoraFluor(IM) 1 absorbs UV light at approximately 340 nm, and emits at approximately 490 nm, 545 nm, 585 nm and 620 nm. It is compatible with common acceptor dyes that absorb at the emission wavelengths of CoraFluor(TM) 1. CoraFluor(TM) 1 can be used for the development of robust and scalable TR-FRET binding assays such as target engagement, ternary complex, protein-protein interaction and protein quantification assays.
• Immunogen: Human recombinant protein fragment corresponding to amino acids 113-370 of human RUVBL2(NP_006657) produced in E.coli.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: RUVBL2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark. Do not freeze.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Notes

CoraFluor (TM) is a trademark of Bio-Techne Corp. Sold for research purposes only under agreement from Massachusetts General Hospital. US patent 2022/0025254

Alternate Names for RUVBL2 Antibody (OTI2B9) [CoraFluor™ 1]

• 48 kDa TATA box-binding protein-interacting protein
• 51 kDa erythrocyte cytosolic protein
• EC 3.6.1
• EC 3.6.4.12,48 kDa TBP-interacting protein
• ECP51TIP49B
• erythrocyte cytosolic protein, 51-KD
• INO80 complex subunit J
• INO80JTAP54-beta
• Repressing pontin 52
• Reptin 52
• REPTIN
• Reptin52
• RuvB (E coli homolog)-like 2
• RuvB-like 2 (E. coli)
• ruvB-like 2
• RVB2
• TBP-interacting protein, 48-KD
• TIH2
• TIP48ECP-51
• TIP49b
• TIP60-associated protein 54-beta

Background

RUVBL2 encodes the second human homologue of the bacterial RuvB gene. Bacterial RuvB protein is a DNA helicase essential for homologous recombination and DNA double-strand break repair. Functional analysis showed that this gene product has both ATPase and DNA helicase activities. This gene is physically linked to the CGB/LHB gene cluster on chromosome 19q13.3, and is very close (55 nt) to the LHB gene, in the opposite orientation. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RUVBL2