RSK3 Antibody (S05-5E4)

Western Blot: RSK3 Antibody (S05-5E4) [NBP3-19811] - Western blot detection of RSK3 in CHO-K1, Hela cell lysates using NBP3-19811 (1:1000 diluted). Predicted band size: 83kDa. Observed band size: 83kDa.

Immunohistochemistry-Paraffin: RSK3 Antibody (S05-5E4) [NBP3-19811] - Immunohistochemical of RSK3 in Human lung cancer tissue using RSK3 antibody at dilution 1/20

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: S05-5E4
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.3 mg/ml

RSK3 Antibody (S05-5E4) Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: A synthetic peptide of human RSK3 (Uniprot # Q15349)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: RPS6KA2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1/20-1/50
  • Immunohistochemistry-Paraffin
  • Western Blot 1/2000
• Theoretical MW: 90 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Concentration: 0.3 mg/ml
• Purity: Affinity purified

Alternate Names for RSK3 Antibody (S05-5E4)

• EC 2.7.11
• EC 2.7.11.1
• HU-2
• MAP kinase-activated protein kinase 1c
• MAPK-activated protein kinase 1c
• MAPKAP kinase 1c
• MAPKAPK1C
• MAPKAPK-1c
• p90-RSK 2
• p90RSK2
• p90-RSK3
• ribosomal protein S6 kinase alpha 2
• ribosomal protein S6 kinase alpha-2
• ribosomal protein S6 kinase, 90kD, polypeptide 2
• ribosomal protein S6 kinase, 90kDa, polypeptide 2
• Ribosomal S6 kinase 3,90 kDa ribosomal protein S6 kinase 2
• RPS6KA2
• RSK
• RSK3
• RSK-3
• RSK3pp90RSK3
• S6K-alpha
• S6K-alpha2
• S6K-alpha-2

Background

RSK3 encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RPS6KA2