RPP20 Antibody

Western Blot: RPP20 Antibody [NBP1-57072] - Human Lung lysate, concentration 0.2-1 ug/ml.

• Reactivity: Hu, Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

RPP20 Antibody Summary

• Immunogen: Synthetic peptides corresponding to POP5 (processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)) The peptide sequence was selected from the middle region of POP5. Peptide sequence IRTCQKFLIQYNRRQLLILLQNCTDEGEREAIQKSVTRSCLLEEEEESGE The peptide sequence for this immunogen was taken from within the described region.
• Specificity: This product is specific to Subunit or Isoform: POP5.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: POP5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1.0 ug/ml
• Application Notes: This is a rabbit polyclonal antibody against POP5 and was validated on Western blot.

Reactivity Notes

Mouse reactivity reported in scientific literature (PMID: 30281021).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 2% Sucrose
• Preservative: 0.09% Sodium Azide
• Purity: Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for RPP20 Antibody

• EC 3.1.26.5
• hPop5
• HSPC004
• processing of precursor 5, ribonuclease P/MRP subunit (S. cerevisiae)
• ribonuclease P/MRP protein subunit POP5
• RPP2
• RPP20

Background

POP5 is a component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends.POP5 is also a component of RNase MRP.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RPP20 Antibody (NBP1-57072)(1)

Publication using NBP1-57072

• Gilbertson S, Federspiel J, Hartenian E et al. Global changes in mRNA abundance drive differential shuttling of RNA binding proteins, linking cytoplasmic RNA degradation to transcription bioRxiv 2018-04-06 [PMID: 30281021] (WB, Human, Mouse)

Bioinformatics

• Gene Symbol: POP5
• Uniprot:
  • Q969H6(Human)