ROR1 Antibody

Immunohistochemistry-Paraffin: ROR1 Antibody [NBP1-52398] - Analysis of anti-ROR1 antibody with human liver at concentration 3 ug/ml.

Immunohistochemistry-Paraffin: ROR1 Antibody [NBP1-52398] - Analysis of anti-ROR1 antibody with human prostate at concentration 3 ug/ml.

Product Discontinued

ROR1 Antibody Summary

• Immunogen: Peptide with sequence C-GNKSQKPYKIDSKQA, from the C-Terminus (near) of the ROR1 protein sequence according to NP_005003.2.
• Specificity: Human ROR1. This antibody is expected to recognize isoform 1 (NP_005003.2) only.
• Predicted Species: Mouse (93%), Rat (93%), Hamster (93%), Canine (93%), Bat (93%), Monkey (93%), Primate (93%), Equine (93%), Rabbit (93%), Bovine (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: ROR1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 3-6 ug/ml
  • Peptide ELISA 1:16000
• Application Notes: IHC: NBP1-52398 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (93%), Turkey (87%), Chicken (87%).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: TBS (pH 7.3) and 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for ROR1 Antibody

• EC 2.7.10.1
• MGC99659
• neurotrophic tyrosine kinase receptor-related 1
• Neurotrophic tyrosine kinase, receptor-related 1
• NTRKR1
• NTRKR1dJ537F10.1
• receptor tyrosine kinase-like orphan receptor 1
• ROR1
• tyrosine-protein kinase transmembrane receptor ROR1

Background

The protein encoded by this gene is a receptor protein tyrosine kinase that modulates neurite growth in the central nervous system. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors. Alternative splicing results in multiple transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ROR1
• Entrez:
  • 4919(Human)
• Uniprot:
  • Q01973()