Rev-erb beta/NR1D2 Antibody (H2729) [Unconjugated]

• Reactivity: Hu
• Applications: WB, IHC, IP, ELISA
• Clone: H2729
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Suitable Sample Type: 23015

Rev-erb beta/NR1D2 Antibody (H2729) [Unconjugated] Summary

• Immunogen: Recombinant human Rev-erb beta/NR1D2
  aa 4-101
• Specificity: This antibody specifically recognizes human Rev-Erb beta and cross-reacts with rat Rev-Erb beta. It does not recognize human Rev-Erb alpha. Not yet tested in other species.
• Source: N/A
• Isotype: IgG3
• Clonality: Monoclonal
• Host: Mouse
• Gene: NR1D2
• Purity Statement: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
  • Immunohistochemistry
  • Immunoprecipitation
  • Direct ELISA

Packaging, Storage & Formulations

• Storage: This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.
• Buffer: A liquid formulation in physiologic saline with 0.1% NaN₃.
• Preservative: 0.1% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rev-erb beta/NR1D2 Antibody (H2729) [Unconjugated]

• BD73
• EAR-1R
• HZF2
• NR1D2
• nuclear receptor subfamily 1 group D member 2
• nuclear receptor subfamily 1, group D, member 2
• Orphan nuclear hormone receptor BD73
• Reverb beta
• Rev-erb beta
• rev-erba-alpha-related receptor
• rev-erb-beta
• RVR
• V-erbA-related protein 1-related

Background

Reverse Orientation the c-ErbA-1 Gene beta (Rev-Erb beta, BD73; NR1D2) is a member of the Orphan Nuclear Receptor family. Rev-Erb beta is expressed in the heart, brain, lung, liver, skeletal muscles, kidney, spleen and testis. Rev-Erb beta plays a broad role in cell proliferation and physiology.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Rev-erb beta/NR1D2 Antibody (PP-H2729-00)(1)

Publication using PP-H2729-00

• H Tong, X Liu, T Li, W Qiu, C Peng, B Shen, Z Zhu NR1D2 Accelerates Hepatocellular Carcinoma Progression by Driving the Epithelial-to-Mesenchymal Transition Onco Targets Ther, 2020;13(0):3931-3942. 2020 [PMID: 32440156] (Western Blot, Human)

Bioinformatics

• Gene Symbol: NR1D2