RalA/RalB Antibody

Product Discontinued

RalA/RalB Antibody Summary

• Immunogen: A synthetic peptide from human Ras-related protein Ral-A (Rala, Ral, Ral-a) conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat and mouse.
• Specificity: Ral-A.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RALA
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Human, rat, mouse.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: IgG purified
• Reconstitution Instructions: Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material. Glycerol may be added (1:1) for additional stability.

Alternate Names for RalA/RalB Antibody

• MGC48949
• RAL
• RalA/RalB
• Ras family small GTP binding protein RALA
• RAS-like protein A
• ras-related protein Ral-A
• v-ral simian leukemia viral oncogene homolog A (ras related)

Background

The product of this gene belongs to the small GTPase superfamily, Ras family of proteins. GTP-binding proteins mediate the transmembrane signaling initiated by the occupancy of certain cell surface receptors. This gene encodes a low molecular mass ras-like GTP-binding protein that shares about 50% similarity with other ras proteins.; SUBUNIT: Interacts with RALBP1 via its effector domain. Interacts with EXOC8 and EXOC2. EXOC2 and EXOC8 have overlapping binding sites and compete for RALA binding. Interacts with Clostridium exoenzyme C3. Interacts with RALGPS1.; SUBCELLULAR LOCATION: Cell membrane; Lipid-anchor; Cytoplasmic side.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RALA
• Entrez:
  • 5898(Human)
  • 56044(Mouse)
  • 81757(Rat)
• Uniprot:
  • P11233()