RAB39 Antibody [Biotin]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Biotin

RAB39 Antibody [Biotin] Summary

• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human RAB39.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RAB39A
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Alternate Names for RAB39 Antibody [Biotin]

• rab-39
• RAB39, member RAS oncogene family
• RAB39A
• rab-related GTP-binding protein
• ras-related protein Rab-39A

Background

Belonging to the small GTPase superfamily/ Rab family, RAB39 plays an important role in cell formation and vesicular trafficking. More specifically, RAB39 proteins are involved in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. It also plays a role in the fusion of phagosomes with lysosomes. Additionally, the main molecular functions include GTP and nucleotide binding. RAB39 interacts with ATG5, CLN3, GABARAPL1, SH3GLB2 and STK11 and diseases include ataxia telangiectasia and malaria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RAB39A