RAB39 Products

Description

Belonging to the small GTPase superfamily/ Rab family, RAB39 plays an important role in cell formation and vesicular trafficking. More specifically, RAB39 proteins are involved in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. It also plays a role in the fusion of phagosomes with lysosomes. Additionally, the main molecular functions include GTP and nucleotide binding. RAB39 interacts with ATG5, CLN3, GABARAPL1, SH3GLB2 and STK11 and diseases include ataxia telangiectasia and malaria.

Bioinformatics

Entrez	54734 Human
Uniprot	AAH28064 Human NP_059986 Human NP_059986.1 Human
Product By Gene ID	54734
Alternate Names	Rab-39 RAB39A ras-related protein Rab-39A rab-related GTP-binding protein rab-39 RAB39, member RAS oncogene family

Diseases related to RAB39

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Stomatitis
Vesicular Stomatitis
Hyperglycemia
Stomach Neoplasms
Diabetic Nephropathy
Kidney Failure, Chronic
Complications Of Diabetes Mellitus
Renal Tubular Acidosis
Carcinoma
Septic Shock
Malignant Neoplasm Of Stomach
Neoplasms
Kidney Diseases

Pathways for RAB39

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Endocytosis
Macropinocytosis
Secretion
Transport
Localization
Clathrin-mediated Endocytosis
Secretory Pathway
Vesicle Transport
Protein Secretion
Pathogenesis
Exocytosis
Rna Interference

Research Areas for RAB39

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Signal Transduction

PTMs for RAB39

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Cleavage

Bioinformatics Tool for RAB39

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