RAB39 Antibody [Alexa Fluor™ Plus 555]

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 555

RAB39 Antibody [Alexa Fluor™ Plus 555] Summary

• Immunogen: Produced in rabbits immunized with a synthetic peptide corresponding to the center region of the Human RAB39.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RAB39A
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen and protein A Affinity-purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for RAB39 Antibody [Alexa Fluor™ Plus 555]

• rab-39
• RAB39, member RAS oncogene family
• RAB39A
• rab-related GTP-binding protein
• ras-related protein Rab-39A

Background

Belonging to the small GTPase superfamily/ Rab family, RAB39 plays an important role in cell formation and vesicular trafficking. More specifically, RAB39 proteins are involved in the maturation and acidification of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis. It also plays a role in the fusion of phagosomes with lysosomes. Additionally, the main molecular functions include GTP and nucleotide binding. RAB39 interacts with ATG5, CLN3, GABARAPL1, SH3GLB2 and STK11 and diseases include ataxia telangiectasia and malaria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RAB39A