Rab11A Antibody (918009) [Alexa Fluor® 532]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: 918009
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 532

Rab11A Antibody (918009) [Alexa Fluor® 532] Summary

• Immunogen: E. coli-derived recombinant human Rab-11A
  Met1-Glu162
  Accession # P62491
• Specificity: Detects human Rab-11A in direct ELISAs and Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Rab11A Antibody (918009) [Alexa Fluor® 532]

• MGC1490
• RAB 11A, member oncogene family
• RAB11
• Rab-11
• Rab11A
• RAB11A, member RAS oncogene family
• YL8
• YL8ras-related protein Rab-11A

Background

Ras-related protein Rab11A is a 25 kDa member of the Rab family of small GTPases.  With more than 40 family members, Rab proteins are regulators of vesicular transport, and their number reflects the complexity of vesicle trafficking.  Rab family members cycle between an inactive GDP-bound form and an active GTP-bound form that recruits to membranes various downstream effectors directly responsible for vesicle formation, migration and fusion.  Rab11A is ubiquitously expressed, with Northern blot analysis detecting highest levels in heart, and lowest levels in liver.  Human Rab11A is 216 amino acids (aa) in length, with residues 214-216 removed in its mature form.  Over aa 1-162, human Rab11A shares 100% identity with mouse and rat Rab11A.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.