QDPR Antibody (M1) - Azide and BSA Free

Western Blot: QDPR Antibody (M1) [H00005860-M02] - Analysis of QDPR expression in transfected 293T cell line by QDPR monoclonal antibody (M02), clone M1.Lane 1: QDPR transfected lysate(25.8 KDa).Lane 2: Non-transfected lysate.

Western Blot: QDPR Antibody (M1) [H00005860-M02] - Analysis of QDPR over-expressed 293 cell line, cotransfected with QDPR Validated Chimera RNAi ( Cat # H00005860-R01V ) (Lane 2) or non-transfected control (Lane 1). Blot probed with QDPR monoclonal antibody (M02), clone M1 (Cat # H00005860-M02 ). GAPDH ( 36.1 kDa ) used as specificity and loading control.

Western Blot: QDPR Antibody (M1) [H00005860-M02] - QDPR monoclonal antibody (M02), clone M1 Analysis of QDPR expression in HL-60.

Sandwich ELISA: QDPR Antibody (M1) [H00005860-M02] - Detection limit for recombinant GST tagged QDPR is approximately 0.1ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, KD
• Clone: M1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

QDPR Antibody (M1) - Azide and BSA Free Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: QDPR (AAH00576, 1 a.a. ~ 244 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MAAAAAAGEARRVLVYGGRGALGSRCVQAFRARNWWVASVDVVENEEASASIIVKMTDSFTEQADQVTAEVGKLLGEEKVDAILCVAGGWAGGNAKSKSLFKNCDLMWKQSIWTSTISSHLATKHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPPGAAAIAVLPVTLDTPMNRKSMPEADFSSWTPLEFLVETFHDWITGKNRPSSGSLIQVVTTEGRTELTPAYF
• Specificity: QDPR - quinoid dihydropteridine reductase
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: QDPR
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Knockdown Validated
  • Sandwich ELISA
  • Western Blot 1:500
• Application Notes: Antibody reactivity against cell lysate and recombinant protein for WB. It has been used for RNAi Validation and ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for QDPR Antibody (M1) - Azide and BSA Free

• DHPR member 1
• DHPR
• HDHPR
• PKU2
• QDPR
• quinoid dihydropteridine reductaseFLJ42391
• SDR33C1

Background

This gene encodes the enzyme dihydropteridine reductase, which catalyzes the NADH-mediated reduction of quinonoid dihydrobiopterin. This enzyme is an essential component of the pterin-dependent aromatic amino acid hydroxylating systems. Mutations in this gene resulting in QDPR deficiency include aberrant splicing, amino acid substitutions, insertions, or premature terminations. Dihydropteridine reductase deficiency presents as atypical phenylketonuria due to insufficient production of biopterin, a cofactor for phenylalanine hydroxylase.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for QDPR Antibody (H00005860-M02)(1)

Publication using H00005860-M02

• Ishii A, Dutta R, Wark GM et al. Human myelin proteome and comparative analysis with mouse myelin. Proc Natl Acad Sci U S A 106(34):14605-10. 2009-08-25 [PMID: 19706548]

Bioinformatics

• Gene Symbol: QDPR
• Entrez:
  • 5860(Human)
• OMIM:
  • 261630(Human)
• Uniprot:
  • AAH00576(Human)