Recombinant Human PTPN4 His Protein

SDS-Page: PTPN4 Recombinant Protein [NBP2-52011] - 15% SDS Page (3 ug)

• Reactivity: Hu
• Applications: PAGE
• Concentration: 1 mg/ml

Recombinant Human PTPN4 His Protein Summary

• Description: A denatured recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 655-913 of Human PTPN4
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MVLTQFDQLY RKKPGMTMSC AKLPQNISKN RYRDISPYDA TRVILKGNED YINANYINME IPSSSIINQY IACQGPLPHT CTDFWQMTWE QGSSMVVMLT TQVERGRVKC HQYWPEPTGS SSYGCYQVTC HSEEGNTAYI FRKMTLFNQE KNESRPLTQI QYIAWPDHGV PDDSSDFLDF VCHVRNKRAG KEEPVVVHCS AGIGRTGVLI TMETAMCLIE CNQPVYPLDI VRTMRDQRAM MIQTPSQYRF VCEAILKVYE

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: PTPN4
• Purity: >85%, by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Application Notes: Denatured protein is most likely not the best option for functional studies. It is better suited for Western Blot (WB) or imaging assays.
• Theoretical MW: 32 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 10% glycerol
• Preservative: No Preservative
• Concentration: 1 mg/ml
• Purity: >85%, by SDS-PAGE

Alternate Names for Recombinant Human PTPN4 His Protein

• EC 3.1.3.48
• MEG
• megakaryocyte phosphatase
• megakaryocyte protein-tyrosine phosphatase
• protein tyrosine phosphatase MEG1
• protein tyrosine phosphatase, non-receptor type 4 (megakaryocyte)
• Protein-tyrosine phosphatase MEG1
• PTPase-MEG1
• PTPMEG
• PTPMEG1
• PTPN4
• tyrosine-protein phosphatase non-receptor type 4

Background

PTPN4 is encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. This PTP has been shown to interact with glutamate receptor delta 2 and epsilon subunits, and is thought to play a role in signalling downstream of the glutamate receptors through tyrosine dephosphorylation. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: PTPN4