PTPN14/PTPD2 Antibody

Product Discontinued

PTPN14/PTPD2 Antibody Summary

• Immunogen: The immunogen for this antibody was a sequence from 580a.a. to 848a.a. from PTPD2(a 1187a.a. long protein)
• Localization: Cytoplasmic
• Specificity: PTPD2
• Clonality: Polyclonal
• Host: Chicken
• Gene: PTPN14
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:200-1:500
• Application Notes: Western Blot: E coli-derived fusion protein as test antigen. Affinity-purified IgY dilution: 1:2000. Goat anti-IgY-HRP dilution: 1:1000. Colorimetric method for signal development.

Reactivity Notes

This antibody is reactive against Human, mouse.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Notes

Chicken products cannot be exported to Canada.

Alternate Names for PTPN14/PTPD2 Antibody

• EC 3.1.3
• EC 3.1.3.48
• MGC126803
• PEZ
• PEZcytoskeletal-associated protein tyrosine phosphatase
• protein tyrosine phosphatase, non-receptor type 14
• Protein-tyrosine phosphatase pez
• PTP36
• PTPN14
• tyrosine-protein phosphatase non-receptor type 14

Background

PTPD2 is a member of the protein tyrosine phosphatase (PTP) family. The PTPs have high substrate specificity for phosphotyrosyl proteins and, at the primary sequence level, share little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. The specific function of this PTP has not yet been determined, although there is evidence to suggest that PTPD2 is involved in regulating cell proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPN14
• Entrez:
  • 5784(Human)
  • 19250(Mouse)
• Uniprot:
  • Q15678(Human)