PTPN14/PTPD2 Antibody (448701) [DyLight 488]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: 448701
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 488

PTPN14/PTPD2 Antibody (448701) [DyLight 488] Summary

• Immunogen: E. coli-derived recombinant human PTPN14
  Leu329-Leu900
  Accession # Q15678.2
• Specificity: Detects endogenous human PTPN14 in Western blots. In Western blots, this antibody does not cross-react with recombinant human (rh) PTPN13 or rhPTPN22.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PTPN14
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PTPN14/PTPD2 Antibody (448701) [DyLight 488]

• EC 3.1.3
• EC 3.1.3.48
• MGC126803
• PEZ
• PEZcytoskeletal-associated protein tyrosine phosphatase
• protein tyrosine phosphatase, non-receptor type 14
• Protein-tyrosine phosphatase pez
• PTP36
• PTPN14
• tyrosine-protein phosphatase non-receptor type 14

Background

PTPD2 is a member of the protein tyrosine phosphatase (PTP) family. The PTPs have high substrate specificity for phosphotyrosyl proteins and, at the primary sequence level, share little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. The specific function of this PTP has not yet been determined, although there is evidence to suggest that PTPD2 is involved in regulating cell proliferation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTPN14