PTP rho/PTPRT Antibody [Alexa Fluor® 700]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Alexa Fluor 700

PTP rho/PTPRT Antibody [Alexa Fluor® 700] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human PTPρ/PTPRT
  Gln26-Lys725
  Accession # O14522
• Specificity: Detects human PTPρ/PTPRT in Western blots. In Western blots, no cross-reactivity with recombinant human LAR, PTPRM, K, S, G or DEP1/CD148 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PTP rho/PTPRT Antibody [Alexa Fluor® 700]

• EC 3.1.3
• EC 3.1.3.48
• KIAA0283RPTPrho
• protein tyrosine phosphatase, receptor type, T
• PTP rho
• PTPRT
• receptor protein tyrosine phosphatase
• Receptor-type tyrosine-protein phosphatase rho
• receptor-type tyrosine-protein phosphatase T
• RPTP-rho
• R-PTP-T

Background

Protein Tyrosine Phosphatase, Receptor-type T (PTPRT), also known as RPTPrho, dephosphorylates tyrosine residues in proteins. PTPRT is present in many tissues, including brain, heart, lung, and colon. Genetic screening of colon cancers indicates that the PTPRT gene has a high incidence of missense mutations that reduce phosphatase activity in the encoded protein. Overexpression of intact PTPRT in cancer cell lines inhibits cell proliferation, suggesting that the phosphatase is a tumor suppressor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.