PTP rho/PTPRT Products

Antibodies
PTP rho/PTPRT Antibody
PTP rho/PTPRT Antibody
AF3697
Species: Hu
Applications: WB
Host: Goat Polyclonal
PTP rho/PTPRT Antibody
PTP rho/PTPRT Antibody
NBP1-81524
Species: Hu, Mu
Applications: WB, IHC, IHC-P
Host: Rabbit Polyclonal
PTP rho/PTPRT Antibody
PTP rho/PTPRT Antibody
NB100-1459
Species: Hu
Applications: WB, PEP-ELISA
Host: Goat Polyclonal
Lysates
PTP rho/PTPRT Overexpression ...
PTP rho/PTPRT Overexpression Lysat...
NBP2-05708
Applications: WB
Proteins
PTP rho/PTPRT Recombinant Pro ...
PTP rho/PTPRT Recombinant Protein ...
NBP1-81524PEP
Species: Hu
Applications: AC
RNAi
PTP rho/PTPRT RNAi
PTP rho/PTPRT RNAi
H00011122-R06
Species: Hu
Applications: RNAi, RNAi SP
PTP rho/PTPRT RNAi
PTP rho/PTPRT RNAi
H00011122-R05
Species: Hu
Applications: RNAi, RNAi SP

Description

PTPRT is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large protein that possesses a PTP domain at C-terminus, and multiple noncatalytic domains, which include a domain with similarity to band 4.1 superfamily of cytoskeletal-associated proteins, a region consisting of five PDZ domains, and a leucine zipper motif. This PTP was found to interact with, and dephosphorylate Fas receptor, as well as I-kappa B-alpha through the PDZ domains, which suggested its role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathway. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported.

Bioinformatics

Entrez Human
Uniprot Human
Human
Human
Product By Gene ID 11122
Alternate Names
  • EC 3.1.3
  • receptor-type tyrosine-protein phosphatase T
  • EC 3.1.3.48
  • receptor protein tyrosine phosphatase
  • RPTP-rho
  • R-PTP-T
  • Receptor-type tyrosine-protein phosphatase rho
  • KIAA0283RPTPrho
  • protein tyrosine phosphatase, receptor type, T

Research Areas for PTP rho/PTPRT

Find related products by research area and learn more about each of the different research areas below.

Protein Phosphatase

PTMs for PTP rho/PTPRT

Learn more about PTMs related to PTP rho/PTPRT.

Phosphorylation
Dephosphorylation

Bioinformatics Tool for PTP rho/PTPRT

Discover related pathways, diseases and genes to PTP rho/PTPRT. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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