PTP beta/zeta/PTPRZ Antibody (122.2)

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Product Details

Summary
Reactivity RtSpecies Glossary
Applications WB, ICC/IF, IP
Clone
122.2
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

PTP beta/zeta/PTPRZ Antibody (122.2) Summary

Immunogen
Embryonic rat brain proteoglycans
Specificity
Receptor Tyrosine Phosphatase Beta (phosphacan)
Isotype
IgM
Clonality
Monoclonal
Host
Mouse
Gene
PTPRZ1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:2500
  • Immunocytochemistry/Immunofluorescence 1:1000-1:2500
  • Immunoprecipitation 1:10-1:500

Reactivity Notes

Rat.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS and 30% Glycerol
Preservative
0.05% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PTP beta/zeta/PTPRZ Antibody (122.2)

  • 3F8 CSPG
  • HPTPZ
  • phosphacan
  • protein tyrosine phosphatase, receptor-type, Z polypeptide 1
  • PTP beta/zeta
  • PTP18
  • PTPRZ
  • PTPRZ1
  • PTPZ
  • receptor-type, zeta polypeptide 1
  • RPTPB
  • RPTPbeta

Background

PTPRB is a member of the protein tyrosine phosphatase (PTP) family. The family comprises at least 37 proteins, characterized by a catalytic phosphatase domain of approximately 240 amino acids, and includes both transmembrane and cytosolic enzymes. PTP1B is a transmembrane PTP. The PTPs have high substrate specificity for phosphotyrosyl proteins, at the primary sequence level sharing little similarity with the protein serine phosphatases, protein threonine phosphatases, or the acid and alkaline phosphatases. PTP beta interacts with and regulates the tyrosine phosphorylation level of catenins, which are critical in physiological and pathological events such as cell migration, adhesion and transformation.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Diseases for PTP beta/zeta/PTPRZ Antibody (NBP1-07068)

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Bioinformatics

Gene Symbol PTPRZ1
Entrez