PSMC6 Antibody - BSA Free

Immunoprecipitation:PSMC6 AntibodyNBP3-29490] -Detection of human PSMC6 by western blot of immunoprecipitates. Samples: Whole cell lysate (1 mg for IP, 20% of IP loaded) from HEK293T cells. Antibodies: Affinity purified rabbit anti-PSMC6 antibody NBP3-29490 used for IP at 6 µg/mg lysate. PSMC6 was also immunoprecipitated by rabbit anti-PSMC6., which recognizes a downstream epitope. For blotting immunoprecipitated PSMC6, was used at 1 µg/ml. Detection: Chemiluminescence with an exposure time of 10 seconds.

• Reactivity: Hu
• Applications: IHC, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PSMC6 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PSMC6 Antibody - BSA Free (NBP3-29490) is a polyclonal antibody validated for use in IHC and IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: between 275 and 325
• Assay Type: [Assay Type]
• Sample Volume: [Sample Volume]
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PSMC6
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunoprecipitation

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-citrate/phosphate buffer, pH 7 to 8
• Preservative: 0.09% Sodium Azide
• Purity: Affinity purified

Alternate Names for PSMC6 Antibody - BSA Free

• 26S protease regulatory subunit 10B
• 26S protease regulatory subunit S10B
• 26S proteasome AAA-ATPase subunit RPT4
• CADP44
• conserved ATPase domain protein 44
• MGC12520
• p42
• P44
• proteasome (prosome, macropain) 26S subunit, ATPase, 6
• Proteasome 26S subunit ATPase 6
• Proteasome subunit p42
• SUG2

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PSMC6