Protein Kinase A Regulatory Subunit II alpha Antibody (2394D) [Alexa Fluor® 594]

• Reactivity: Hu, Mu
• Applications: WB, IHC, ICC/IF
• Clone: 2394D
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor 594

Protein Kinase A Regulatory Subunit II alpha Antibody (2394D) [Alexa Fluor® 594] Summary

• Additional Information: Recombinant Monoclonal Antibody.
• Immunogen: Synthetic peptide containing Human/Mouse PKA RIIα
  Accession # P13861
• Specificity: Detects human PKA RII alpha in direct ELISAs. Detects human and mouse PKA RII alpha in Western blots.
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunohistochemistry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Protein Kinase A Regulatory Subunit II alpha Antibody (2394D) [Alexa Fluor® 594]

• cAMP-dependent protein kinase regulatory subunit RII alpha
• cAMP-dependent protein kinase type II-alpha regulatory subunit
• PKA RII alpha
• PKR2
• PRKAR2
• PRKAR2A
• protein kinase A, RII-alpha subunit
• protein kinase, cAMP-dependent, regulatory subunit type II alpha

Background

PRKAR2 is a regulatory subunit of the cAMP-dependent protein kinases involved in CAMP signaling in cells.  Four types of regulatory chains are found and their expression varies among tissues.  In some cases expression is constitutive and in other cases it is inducible.  PRKAR2 seems to be involved in both endosome-to-Golgi and Golgi-to-ER transport.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.