Proteasome 19S S3 Antibody (OTI2A2) [PE]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Ca, Pm, PmSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clone
OTI2A2
Clonality
Monoclonal
Host
Mouse
Conjugate
PE

Order Details

Proteasome 19S S3 Antibody (OTI2A2) [PE] Summary

Immunogen
Full length recombinant protein of human Proteasome 19S S3 (NP_002800) produced in HEK293T cells.
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
PSMD3
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Flow Cytometry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Alternate Names for Proteasome 19S S3 Antibody (OTI2A2) [PE]

  • 26S proteasome regulatory subunit RPN3
  • 26S proteasome regulatory subunit S3
  • P58
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 3
  • Proteasome subunit p58
  • Rpn3
  • S3, 26S proteasome non-ATPase regulatory subunit 3
  • tissue specific transplantation antigen 2
  • TSTA2

Background

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PSMD3