Proteasome 19S S3 Products

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. (provided by RefSeq)

Bioinformatics

Entrez	5709 Human
Uniprot	AAH20518 Human NM_002809 Human NP_002800 Human O43242 Human
Product By Gene ID	5709
Alternate Names	26S proteasome regulatory subunit RPN3 26S proteasome regulatory subunit S3 P58 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3 Proteasome subunit p58 RPN3 Rpn3 S3, 26S proteasome non-ATPase regulatory subunit 3 tissue specific transplantation antigen 2 TSTA2

Research Areas for Proteasome 19S S3

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Neuroscience
Ubiquitin Proteasome Pathway