Proteasome 19S S3 Products

Description

The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. (provided by RefSeq)

Bioinformatics

Entrez	5709 Human
Uniprot	NP_002800 Human O43242 Human NM_002809 Human AAH20518 Human
Product By Gene ID	5709
Alternate Names	26S proteasome regulatory subunit RPN3 TSTA2 Proteasome subunit p58 RPN3 tissue specific transplantation antigen 2 S3, 26S proteasome non-ATPase regulatory subunit 3 Rpn3 P58 26S proteasome regulatory subunit S3 proteasome (prosome, macropain) 26S subunit, non-ATPase, 3

Diseases related to Proteasome 19S S3

Discover more about diseases related to Proteasome 19S S3.

Asthma
Neoplasms
Sezary Syndrome
Crohn Disease
Lymphoma, T-cell, Cutaneous
Lymphoma
Cytogenetic Abnormality
Childhood Asthma
T-cell Lymphoma

Pathways for Proteasome 19S S3

View related products by pathway and learn more about each of the pathways below.

Pathogenesis
Secretion
Lymphocyte Activation

Research Areas for Proteasome 19S S3

Find related products by research area and learn more about each of the different research areas below.

Neuroscience
Ubiquitin Proteasome Pathway

Bioinformatics Tool for Proteasome 19S S3

Discover related pathways, diseases and genes to Proteasome 19S S3. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.