Human Proprotein Convertase 9/PCSK9 ELISA Kit (Colorimetric)

Product Discontinued

Human Proprotein Convertase 9/PCSK9 ELISA Kit (Colorimetric) Summary

• Description: Quality control test: Standard curve. Human PCSK9 ELISA kit is a sandwich enzyme immunoassay for the quantitative measurement of human PCSK9 in serum, plasma, cell culture medium, and other biological media.
• Standard Curve Range: 0.16 to 10 ng/mL
• Sensitivity: 0.154 ng/mL
• Assay Type: Sandwich ELISA
• Inter-Assay: CV% < 4.32%
• Intra-Assay: CV% < 1.96%
• Spike Recovery: 94.23%
• Sample Volume: 100 uL (1:100 prediluted)
• Kit Type: ELISA Kit (Colorimetric)
• Gene: PCSK9

Applications/Dilutions

• Dilutions:
  • ELISA
  • Quantification
• Application Notes: Useful for quantification.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Human Proprotein Convertase 9/PCSK9 ELISA Kit (Colorimetric)

• EC 3.4.21
• EC 3.4.21.111
• FH3
• FH3neural apoptosis regulated convertase 1
• FHCL3
• HCHOLA3
• hypercholesterolemia, autosomal dominant 3
• LDLCQ1
• NARC1
• NARC-1
• NARC-1convertase subtilisin/kexin type 9 preproprotein
• NARC1EC 3.4.21.-
• Neural apoptosis-regulated convertase 1
• PC9
• PCSK9
• Proprotein Convertase 9
• proprotein convertase subtilisin/kexin type 9
• Subtilisin/kexin-like protease PC9

Background

PCSK9 encodes a proprotein convertase belonging to the proteinase K subfamily of the secretory subtilase family. The encoded protein is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the endoplasmic reticulum. The protein may function as a proprotein convertase. This protein plays a role in cholesterol homeostasis and may have a role in the differentiation of cortical neurons. Mutations in this gene have been associated with a third form of autosomal dominant familial hypercholesterolemia (HCHOLA3).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for Proprotein Convertase 9/PCSK9 ELISA Kit (KA1072)(4)

Publications using KA1072

• Hosseni B, Shabani M, Mohammadi A et al. Plasma PCSK9 level affects passively LAMP-2 expression; an evidence of transcription network. Gene Reports Jul 8 2016
• Soltanmohammadi E, Piran S, Mohammadi A et al. Serum sdLDL-C and Cellular SREBP2-Dependent Cholesterol Levels; Is There a Challenge on Targeting PCSK9? Journal of Medical Biochemistry Sep 20 2016
• Hosseni B, Shabani M, Mohammadi A et al. Plasma PCSK9 level affects passively LAMP-2 expression; an evidence of transcription network. Gene Reports. 2016-01-01
• Soltanmohammadi E, Piran S, Mohammadi A et al. Serum sdLDL-C and Cellular SREBP2-Dependent Cholesterol Levels; Is There a Challenge on Targeting PCSK9? Journal of Medical Biochemistry. 2016-11-02 [PMID: 28670193]

FAQs for Proprotein Convertase 9/PCSK9 ELISA Kit (KA1072). (Showing 1 - 1 of 1 FAQs).

1. What is the difference between the Quantikine and Duoset ELISA kits?
   • Our Quantikine kits are fully optimized and validated for the sample types listed on the product specific webpage and datasheet, as this can vary between kits. Each kit is supplied ready to use with one pre-coated 96-well plate, a detection antibody directly conjugated to HRP, and all other necessary reagents. These kits are ideal for researchers who want the convenience of a ready to use and optimized ELISA product. Some of these kits are also available prepackaged in larger 6 and 50 plate sizes.Our DuoSet Kits, in contrast, are ELISA development kits containing the capture and detection antibody, the mass-value calibrated standard, and streptavidin-HRP to prepare approximately 5 or 15 plates. Ancillary reagents will need to be used/purchased, and for most kits, we will recommend one of our Ancillary Reagent Kits, which contain the reagents we use ourselves in-house. DuoSet kits are validated only for cell culture supernatant samples and therefore require further development and validation for accurate measurement in more complex samples such as serum and plasma. Our DuoSet Kits offer an economical, flexible alternative for the experienced ELISA user.

Bioinformatics

• Gene Symbol: PCSK9