PRKAG3 Antibody - BSA Free

Western Blot: PRKAG3 Antibody [NBP3-41543] - Sample: Recombinant protein.

Immunohistochemistry-Paraffin: PRKAG3 Antibody [NBP3-41543] - Used in DAB staining on fromalin fixed paraffin- embedded Kidney tissue

• Reactivity: Mu
• Applications: WB, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.5 mg/ml

PRKAG3 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PRKAG3 Antibody - BSA Free (NBP3-41543) is a polyclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Immunized with recombinant Mouse PRKAG3 (Uniprot#: Q8BGM7; Val238-Val467 (Uniprot#: Q8BGM7)
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PRKAG3
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 5-20ug/mL
  • Western Blot 0.2-2ug/mL

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS, pH7.4, 50% glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Antigen and protein A Affinity-purified

Alternate Names for PRKAG3 Antibody - BSA Free

• 5'-AMP-activated protein kinase subunit gamma-3
• AMPK gamma 3
• AMPK gamma-3 chain
• AMPK gamma3
• AMPK subunit gamma-3
• AMPKG3
• AMPKG3,5'-AMP-activated protein kinase, gamma-3 subunit
• PRKAG3
• protein kinase, AMP-activated, gamma 3 non-catalytic subunit

Background

PRKAG3 is encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PRKAG3