PRG-1/LPPR4 Antibody (368701) [Alexa Fluor® 488]

• Applications: WB
• Clone: 368701
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 488

PRG-1/LPPR4 Antibody (368701) [Alexa Fluor® 488] Summary

• Immunogen: E. coli-derived recombinant human PRG‑1/LPPR4
  Ser285-Asp715
  Accession # AAO85400
• Specificity: Detects PRG‑1/LPPR4 in direct ELISAs and Western blots.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

PRG-1 (plasticity-related gene-1) is a member of the lipid phosphate phosphatase-related protein (LPR) family. The 715 aa protein has a calculated (unglycosylated) molecular weight of 78 kDa. LPR members have six N-terminal transmembrane sequences and a C-terminal cytoplasmic domain thought to regulate phospholipid phosphatase activity. PRG-1 is expressed on axons in the hippocampus and is upregulated during axonal outgrowth. The C-terminal domain of human PRG-1 (amino acids 285‑715) shares 95% and 94% amino acid identity with mouse and rat PRG-1, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.