PPP2R2D Antibody

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Western Blot: PPP2R2D Antibody [NBP1-74170] - Titration: 1.0 ug/ml Positive Control: Mouse Brain.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

PPP2R2D Antibody Summary

Immunogen
Synthetic peptides corresponding to the C terminal of Ppp2r2d. Immunizing peptide sequence RRDVTLEASRENSKPRASLKPRKVCTGGKRKKDEISVDSLDFNKKILHTA. The peptide sequence for this immunogen was taken from within the described region.
Specificity
This product is specific to Subunit or Isoform: B delta isoform.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PPP2R2D
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1.0 ug/ml
Application Notes
This is a rabbit polyclonal antibody against Ppp2r2d and was validated on Western blot.
Theoretical MW
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS and 2% Sucrose
Preservative
0.09% Sodium Azide
Purity
Immunogen affinity purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for PPP2R2D Antibody

  • KIAA1541
  • MDS026
  • PP2A subunit B isoform B55-delta
  • PP2A subunit B isoform delta
  • PP2A subunit B isoform PR55-delta
  • PP2A subunit B isoform R2-delta
  • protein phosphatase 2, regulatory subunit B, delta isoform
  • protein phosphatase 2, regulatory subunit B, delta
  • serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B deltaisoform

Background

Ppp2r2d is a B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol PPP2R2D
Uniprot