PPP2R2D Products

Description

Ppp2r2d is a B regulatory subunit of protein phosphatase 2A (PP2A) that plays a key role in cell cycle by controlling mitosis entry and exit. The activity of PP2A complexes containing PPP2R2D (PR55-delta) fluctuate during the cell cycle: the activity is high in interphase and low in mitosis. During mitosis, activity of PP2A is inhibited via interaction with phosphorylated ENSA and ARPP19 inhibitors. Within the PP2A complexes, the B regulatory subunits modulate substrate selectivity and catalytic activity, and also may direct the localization of the catalytic enzyme to a particular subcellular compartment.

Bioinformatics

Uniprot	Q925E7 Mouse
Product By Gene ID	55844
Alternate Names	KIAA1541 MDS026 PP2A subunit B isoform B55-delta PP2A subunit B isoform delta PP2A subunit B isoform PR55-delta PP2A subunit B isoform R2-delta protein phosphatase 2, regulatory subunit B, delta isoform protein phosphatase 2, regulatory subunit B, delta serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B deltaisoform

Research Areas for PPP2R2D

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Protein Phosphatase