PPFIA3 Antibody [Janelia Fluor® 525]

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Janelia Fluor 525

PPFIA3 Antibody [Janelia Fluor® 525] Summary

• Immunogen: PPFIA3 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human PPFIA3. The immunogen is located within amino acids 1100 - 1150 of PPFIA3. Amino Acid Squence: LGTDRRLDEDSAKSFSR
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PPFIA3
• Purity: Peptide affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Peptide affinity purified

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for PPFIA3 Antibody [Janelia Fluor® 525]

• KIAA0654liprin
• liprin-alpha-3
• LPNA3liprin-alpha 3
• MGC126567
• MGC126569
• Protein tyrosine phosphatase receptor type f polypeptide-interacting proteinalpha-3
• protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interactingprotein (liprin), alpha 3
• protein tyrosine phosphatase, receptor type, f polypeptide, alpha 3
• PTPRF-interacting protein alpha-3

Background

PPFIA3, also known as Liprin-alpha-3, has a 1,194 amino acid long isoform that is 133kDa and a slightly shorter 1,185 amino acid isoform that is approximately 132kDa. PPFIA3 is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. PPFIA3 is localized to the cytoplasm and cell surface, and is highly expressed in the brain. As a member of the Liprin family, research shows that PPFIA3 may play a role in the disassembly of focal adhesions. Current research surrounding PPFIA3 shows that it may be implicated in various diseases and disorders including cerebritis, cerebral malformations, cocaine abuse, neuronitis and epilepsy. PPFIA3 has also been shown to interact with GIT1, PTPRS, PIK3R1, ERC2, and PPFIBP2.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PPFIA3