POU3F2/OCT7 Antibody (761340) [DyLight 488]

• Reactivity: Hu
• Applications: WB
• Clone: 761340
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 488

POU3F2/OCT7 Antibody (761340) [DyLight 488] Summary

• Immunogen: E. coli-derived recombinant human POU3F2
  Asn7-His59
  Accession # P20265
• Specificity: Detects human POU3F2 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human (rh) POU5F1 or rhPOU4F3 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: POU3F2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for POU3F2/OCT7 Antibody (761340) [DyLight 488]

• Brain-2
• Brain-specific homeobox/POU domain protein 2
• BRN2
• brn-2
• BRN2brain-2
• Nervous system-specific octamer-binding transcription factor N-Oct-3
• Oct7
• oct-7
• OCT7POU domain class 3, transcription factor 2
• Octamer-binding protein 7
• Octamer-binding transcription factor 7
• OTF7
• OTF-7
• POU class 3 homeobox 2
• POU domain, class 3, transcription factor 2
• POU3F2
• POUF3

Background

POU3F2 belongs to a large family of transcription factors that bind to the octameric DNA sequence ATGCAAAT. Most of these proteins share a highly homologous region, referred to as the POU domain, that occurs in several mammalian transcription factors, including the octamer-binding proteins Oct1 (POU2F1; MIM 164175) and Oct2 (POU2F2; MIM 164176) and the pituitary protein Pit1 (PIT1; MIM 173110). Class III POU genes are expressed predominantly in the central nervous system (CNS). It is likely that CNS-specific transcription factors such as these play an important role in mammalian neurogenesis by regulating their diverse patterns of gene expression (Schreiber et al., 1993 [PubMed 8441633]; Atanasoski et al., 1995 [PubMed 7601453]).[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: POU3F2