POP1 Antibody

Product Discontinued

POP1 Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 925 and 975 of human processing of precursor 1 using the numbering given in entry NP_055844.1 (GeneID 10940).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: POP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:1000 - 1:5000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:2000 - 1:10000
  • Immunoprecipitation 5-10 ug/mg lysate
• Application Notes: It is not recommended for western analysis. Immunohistochemistry 1:2,000 to 1:10,000. Epitope retrieval with citrate buffer pH6.0 is recommended for FFPE tissue sections.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for POP1 Antibody

• EC 3.1.26.5
• hPOP1
• KIAA0061
• MGC17365
• processing of precursor 1, ribonuclease P/MRP subunit (S. cerevisiae)
• processing of precursors 1
• ribonucleases P/MRP protein subunit POP1

Background

POP1 (processing of precursor 1) is a subunit of both the ribonuclease P and RNase MRP holoenzymes which are involved in 5'-end maturation of precursor tRNAs (pre-tRNAs). POP1 has been found to be an autoantigen in patients suffering from connective tissue diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: POP1
• Entrez:
  • 10940(Human)
• Uniprot:
  • NP_055844.1(Human)