PNMA2 Antibody Pair

Product Discontinued

PNMA2 Antibody Pair Summary

• Description: Quality control test: Standard curve using recombinant protein (H00010687-P01) as an analyte. This antibody pair set comes with matched antibody pair to detect and quantify protein level of human PNMA2.
  
  
• Capture antibody: mouse monoclonal anti-PNMA2 (100 ug)
• Detection antibody: biotinylated mouse monoclonal anti-PNMA2 IgG2a Kappa (50 ug)
• Standard Curve Range: 0.3 ng/ml to 100 ng/ml
• Assay Type: Sandwich ELISA
• Clonality: Monoclonal
• Gene: PNMA2

Applications/Dilutions

• Dilutions:
  • Sandwich ELISA 0.3 ng/ml - 100 ng/ml

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: 1x PBS, pH 7.4
• Preservative: No Preservative

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PNMA2 Antibody Pair

• MA2KIAA0883
• MM2
• Onconeuronal antigen Ma2
• paraneoplastic antigen MA2,40 kDa neuronal protein
• Paraneoplastic neuronal antigen MM2
• retrotransposon gag domain containing 2
• RGAG2

Background

In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a para-neoplastic disorder. Two proteins, Ma1 and Ma2, were discovered by presence of autoantibodies against them. Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum. These autoantibodies were used to clone Ma2, which codes for a protein (Ma2) that was recognized by serum from the 10 patients, but not by serum from 344 control subjects. Ma2 was selectively expressed by normal brain tissue and by the testicular tumors of the patients. Ma2 shares homology with Ma1, a "brain-testis-cancer" gene related to other para-neoplastic syndromes and tumors.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are guaranteed for 6 months from date of receipt.

Bioinformatics

• Gene Symbol: PNMA2