WB, IHC, IHC-PHost:
Host: Rabbit Polyclonal
WB, ELISA, PA, AP
In patients with cancer, symptoms of limbic and brain-stem dysfunction may result from a para-neoplastic disorder. Two proteins, Ma1 and Ma2, were discovered by presence of autoantibodies against them. Antibodies to Ma1 and Ma2 proteins identify a paraneoplastic disorder that affects the limbic system, brain stem, and cerebellum. These autoantibodies were used to clone Ma2, which codes for a protein (Ma2) that was recognized by serum from the 10 patients, but not by serum from 344 control subjects. Ma2 was selectively expressed by normal brain tissue and by the testicular tumors of the patients. Ma2 shares homology with Ma1, a "brain-testis-cancer" gene related to other para-neoplastic syndromes and tumors.
|Product By Gene ID
- Paraneoplastic neuronal antigen MM2
- retrotransposon gag domain containing 2
- Onconeuronal antigen Ma2
- paraneoplastic antigen MA2,40 kDa neuronal protein
Pathways for PNMA2
View related products by pathway and learn more about each of the pathways below.Pathogenesis
Research Areas for PNMA2
Find related products by research area and learn more about each of the different research areas below.Stem Cell Markers
Bioinformatics Tool for PNMA2
Discover related pathways, diseases and genes to PNMA2. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.