PMS1 Antibody (CL14436) [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: WB
• Clone: CL14436
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 350

PMS1 Antibody (CL14436) [Alexa Fluor® 350] Summary

• Immunogen: This antibody was generated using a synthetic peptide of P54277, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: PMS1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

Alexa Fluor (R) products are provided under an intellectual property license from Life Technologies Corporation. The purchase of this product conveys to the buyer the non-transferable right to use the purchased product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components, or any materials made using the product or its components, in any activity to generate revenue, which may include, but is not limited to use of the product or its components: (i) in manufacturing; (ii) to provide a service, information, or data in return for payment; (iii) for therapeutic, diagnostic or prophylactic purposes; or (iv) for resale, regardless of whether they are resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5791 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@lifetech.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PMS1 Antibody (CL14436) [Alexa Fluor® 350]

• DKFZp781M0253
• FLJ98259
• HNPCC3
• hPMS1
• human homolog of yeast mutL
• mismatch repair gene PMSL1
• PMS1 postmeiotic segregation increased 1 (S. cerevisiae)
• PMS1 protein homolog 1
• PMSL1DNA mismatch repair protein PMS1
• postmeiotic segregation increased (S. cerevisiae) 1
• rhabdomyosarcoma antigen MU-RMS-40.10B
• rhabdomyosarcoma antigen MU-RMS-40.10E

Background

PMS1 was identified by its homology to a yeast protein involved in DNA mismatch repair. A role for this protein in mismatch repair has not been proven. However, the protein forms heterodimers with MLH1, a DNA mismatch repair protein, and some cases of hereditary nonpolyposis colorectal cancer have been found to have mutations in the gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PMS1