PLUNC Antibody [Biotin]

• Reactivity: Hu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Biotin
• Concentration: LYOPH

PLUNC Antibody [Biotin] Summary

• Immunogen: E. coli-derived recombinant human PLUNC
  Gln20-Val256
  Accession # Q9NP55
• Specificity: Detects human PLUNC in Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: BPIFA1
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for PLUNC Antibody [Biotin]

• bA49G10.5
• BPIFA1
• ligand-binding protein RYA3
• LPLUNC3
• Lung-specific protein X
• LUNX
• LUNXNASG
• Nasopharyngeal carcinoma-related protein
• Palate lung and nasal epithelium clone protein
• palate, lung and nasal epithelium associated
• palate, lung and nasal epithelium carcinoma associated
• PLUNC
• protein Plunc
• Secretory protein in upper respiratory tracts
• SPLUNC1
• SPLUNC1SPURT
• tracheal epithelium enriched protein
• Tracheal epithelium-enriched protein
• Von Ebner protein Hl

Background

PLUNC, also named SPLUNC1, is a secreted protein that is expressed in the secretory ducts and submucosal glands of tracheobronchial tissues. It is structurally related to bactericidal/permeability-increasing protein (BPI) and lipopolysaccaride binding protein (LBP), which are central to the host defense against gram-negative bacteria. PLUNC belongs to the short subfamily of PLUNC family proteins and have homology only to the N-terminal domains of BPI. PLUNC may function in the innate immune response against bacteria.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PLUNC Antibody (BAF1897)(1)

Publication using BAF1897

• Wright PL, Yu J, Di YP Epithelial reticulon 4B (Nogo-B) is an endogenous regulator of Th2-driven lung inflammation. J. Exp. Med., 2010-10-25;207(12):2595-607. 2010-10-25 [PMID: 20975041] (IHC-P, Western Blot, Human)

Bioinformatics

• Gene Symbol: BPIFA1
• Uniprot:
  • Q9NP55()