PLK4 Antibody (1C8)

Western Blot: PLK4 Antibody (1C8) [H00010733-M01] - Western Blot analysis of PLK4 expression in Hela NE ( Cat # L013V3 ).

Sandwich ELISA: PLK4 Antibody (1C8) [H00010733-M01] - Detection limit for recombinant GST tagged PLK4 is approximately 0.03ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA, S-ELISA
• Clone: 1C8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated

PLK4 Antibody (1C8) Summary

• Immunogen: PLK4 (AAH36023, 1 a.a. ~ 110 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. MATCIGEKIEDFKVGNLLGKGSFAGVYRAESIHTGLEVAIKMIDKKAMYKAGMVQRVQNEVKIHCQLKHPSILELYNYFEDSNYVYLVLEMCHNGEMNRYLKNRVKPFSE
• Specificity: PLK4 (1C8)
• Isotype: IgG1 Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PLK4
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Sandwich ELISA
  • Western Blot
• Application Notes: Antibody reactive against cell lysate for western blot. It has also been used for ELISA.

Reactivity Notes

Human. Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PLK4 Antibody (1C8)

• EC 2.7.11.21
• PLK4
• PLK-4
• polo-like kinase 4 (Drosophila)
• Polo-like kinase 4
• polo-like kinase 4SAKSTK18serine/threonine kinase 18
• SAK
• serine/threonine protein kinase SAK
• Serine/threonine-protein kinase 18
• serine/threonine-protein kinase PLK4
• Serine/threonine-protein kinase Sak
• Snk akin kinase
• STK18

Background

This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to centrioles, complex microtubule-based structures found in centrosomes, and regulates centriole duplication during the cell cycle.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PLK4 Antibody (H00010733-M01)(1)

Publication using H00010733-M01

• Rizki, A et al. Polo-like Kinase 1 Is Involved in Invasion through Extracellular Matrix. Cancer Res67:11106-11110. 2007-01-01 [PMID: 18056432]

Bioinformatics

• Gene Symbol: PLK4
• Entrez:
  • 10733(Human)
• OMIM:
  • 605031(Human)
• Uniprot:
  • AAH36023(Human)