Plexin B2 Antibody (537219) [HRP]

• Reactivity: Hu
• Applications: WB
• Clone: 537219
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: HRP

Plexin B2 Antibody (537219) [HRP] Summary

• Description: This conjugate is made on demand and is not held in inventory. Each order represents a unique lot. All conjugates are generated using validated conjugation protocols and meet strict degree of labeling (F/P) specifications; additional information is available upon request. The antibody concentration is provided on the individual product label.
  
  For specialized conjugation needs, like large quantities, specific concentrations, and defined F/P ratios, bulk and custom antibody conjugation services are available.
• Immunogen: Chinese hamster ovary cell line CHO-derived recombinant human Plexin B2
  Leu20-Arg1160
  Accession # O15031
• Specificity: Detects human Plexin B2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant mouse Plexin B2 or recombinant human Plexin B3 is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: PLXNB2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Recommended applications are based on validated applications from the unconjugated base product MAB53292. This conjugated antibody is not kept in inventory and is made to order using validated conjugation protocols.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Protein A or G purified from hybridoma culture supernatant

Alternate Names for Plexin B2 Antibody (537219) [HRP]

• MM1
• MM1KIAA0315dJ402G11.3
• Nbla00445
• PLEXB2
• Plexin B2
• plexin-B2
• PLXNB2

Background

Plexin B2, also known by its gene name PLXNB2, has 1,838 amino acids and is approximately 205kDa. Plexin B2 is a member of the Plexin family, and localizes to the cell membrane as a transmembrane receptor. Plexin B2 is a receptor for Semaphorins, such as SEMA4C, SEMA4D and SEMA4G, and is implicated in cell migration, cell-cell signaling, and axon guidance. Current research on Plexin B2 is being performed in relation to several diseases and disorders including leukemia, neuronitis and Situs inversus. Plexin B2 has also been shown to have interactions with MET, PFDN1, HMOX2, MST1R, and MLF1IP in the axon guidance pathway.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLXNB2