PLC-beta 1 Antibody - BSA Free

Immunohistochemistry-Paraffin: PLC-beta 1 Antibody [NBP2-37966] - Staining of human pancreas shows low expression as expected.

Immunohistochemistry: PLC-beta 1 Antibody [NBP2-37966] - Staining of human lateral ventricle shows moderate cytoplasmic and nucleolar positivity in neuronal cells.

Immunohistochemistry-Paraffin: PLC-beta 1 Antibody [NBP2-37966] - Staining of human cerebral cortex shows high expression.

Immunohistochemistry-Paraffin: PLC-beta 1 Antibody [NBP2-37966] - Staining in human cerebral cortex and pancreas tissues using anti-PLCB1 antibody. Corresponding PLCB1 RNA-seq data are presented for the same tissues.

• Reactivity: Hu, Mu, Rt
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PLC-beta 1 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PLC-beta 1 Antibody - BSA Free (NBP2-37966) is a polyclonal antibody validated for use in IHC. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against a recombinant protein corresponding to amino acids: EEEVKKEADPGETPSEAPSEARTTPAENGVNHTTTLTPKPPSQALHSQPAPGSVKAPAKTEDLIQSVLTEVEAQTIEELKQQKSFVK
• Predicted Species: Mouse (93%), Rat (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PLCB1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:2500 - 1:5000
  • Immunohistochemistry-Paraffin 1:2500 - 1:5000
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  PLC-beta 1 Protein (NBP2-37966PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for PLC-beta 1 Antibody - BSA Free

• EC 3.1.4.11
• EIEE12
• FLJ45792
• inositoltrisphosphohydrolase
• KIAA05811-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1
• monophosphatidylinositol phosphodiesterase
• phosphoinositidase C
• Phosphoinositide phospholipase C-beta-1
• phospholipase C, beta 1 (phosphoinositide-specific)
• Phospholipase C-beta-1
• Phospholipase C-I
• PI-PLC
• PLC-154
• PLC154,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
• PLCB1
• PLCB1A
• PLCB1B
• PLCbeta 1
• PLC-beta 1
• PLC-beta-1
• PLC-I
• PLC-I1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
• triphosphoinositide phosphodiesterase

Background

Phospholipase C beta 1 is encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLCB1
• Uniprot:
  • Q9NQ66()