PLC-beta 1 Antibody (S03-6E6)

Western Blot: PLC-beta 1 Antibody (S03-6E6) [NBP3-19739] - Western blot detection of PLC-beta 1 in Rat Brain lysates using NBP3-19739 (1:500 diluted). Predicted band size: 138kDa. Observed band size: 138kDa.

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: S03-6E6
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 0.3 mg/ml

PLC-beta 1 Antibody (S03-6E6) Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant protein of mouse PLC-beta 1 (Uniprot # Q9Z1B3)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: PLCB1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1/1000
• Theoretical MW: 138 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA
• Preservative: 0.01% Sodium Azide
• Concentration: 0.3 mg/ml
• Purity: Affinity purified

Alternate Names for PLC-beta 1 Antibody (S03-6E6)

• EC 3.1.4.11
• EIEE12
• FLJ45792
• inositoltrisphosphohydrolase
• KIAA05811-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta 1
• monophosphatidylinositol phosphodiesterase
• phosphoinositidase C
• Phosphoinositide phospholipase C-beta-1
• phospholipase C, beta 1 (phosphoinositide-specific)
• Phospholipase C-beta-1
• Phospholipase C-I
• PI-PLC
• PLC-154
• PLC154,1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase beta-1
• PLCB1
• PLCB1A
• PLCB1B
• PLCbeta 1
• PLC-beta 1
• PLC-beta-1
• PLC-I
• PLC-I1-phosphatidyl-D-myo-inositol-4,5-bisphosphate
• triphosphoinositide phosphodiesterase

Background

Phospholipase C beta 1 is encoded by this gene catalyzes the formation of inositol 1,4,5-trisphosphate and diacylglycerol from phosphatidylinositol 4,5-bisphosphate. This reaction uses calcium as a cofactor and plays an important role in the intracellular transduction of many extracellular signals. This gene is activated by two G-protein alpha subunits, alpha-q and alpha-11. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PLCB1