Plakophilin 2 Antibody - BSA Free

Western Blot: Plakophilin 2 Antibody [NBP3-42354] - Sample: Cavia Salivary gland lysate Primary Ab: 5ug/ml NBP3-42354; Second Ab: 0.2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Immunohistochemistry-Paraffin: Plakophilin 2 Antibody [NBP3-42354] - DAB staining on IHC-P; Samples: Human Liver Tissue; Primary Ab: 10ug/ml NBP3-42354; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

Immunohistochemistry-Paraffin: Plakophilin 2 Antibody [NBP3-42354] - DAB staining on IHC-P; Samples: Human Stomach Tissue; Primary Ab: 10ug/ml NBP3-42354; Second Ab: 2ug/mL HRP-Linked Caprine Anti-Rabbit IgG Polyclonal Antibody

• Reactivity: Hu, Mu, Gp
• Applications: WB
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 0.5 mg/ml

Plakophilin 2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Plakophilin 2 Antibody - BSA Free (NBP3-42354) is a polyclonal antibody validated for use in WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Immunogen sequence: Asp571-Ala849 (Uniprot#: Q99959)
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PKP2
• Purity: Antigen and protein A Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.5-5ug/mL

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.01M PBS, pH7.4, 50% glycerol
• Preservative: 0.05% Proclin 300
• Concentration: 0.5 mg/ml
• Purity: Antigen and protein A Affinity-purified

Alternate Names for Plakophilin 2 Antibody - BSA Free

• ARVD9
• MGC177501
• plakophilin 2
• plakophilin-2

Background

Plakophilins 1, 2, 3 and 4 (PKP1-4) influence development and participate in linking cadherins to cytoskeletal intermediate filaments. Plakophilins 1-4 contain arm-repeat (armadillo) domains and localize to nuclei and cell desmosomes (cell-cell junctions found in suprabasal layers of stratifying epithelia that undergo mechanical stress). Plakophilin 1 mediates increases in desmosomal protein content, desmosome assembly and regulation of cell migration. Plakophilin 2 is important for desmosome assembly and is an essential morphogenic factor and architectural component of the heart. Plakophilin 4 is a component of desmosomal adhesion plaques that regulates junctional plaque organization and cadherin function.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PKP2