PKN1 Antibody (1A4)

Product Discontinued

PKN1 Antibody (1A4) Summary

• Description: Quality control test: Antibody Reactive Against Recombinant Protein.
• Immunogen: PKN1 (AAH40061 462 a.a. - 615 a.a.) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. LDMEPQGCLVAEVTFRNPVIERIPRLRRQKKIFSKQQGKAFQRARQMNIDVATWVRLLRRLIPNATGTGTFSPGASPGSEARTTGDISVEKLNLGTDSDSSPQKSSRDPPSSPSSLSSPIQESTAPELPSETQETPGPALCSPLRKSPLTLEDF
• Specificity: PKN1 - protein kinase N1 (1A4)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: PKN1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PKN1 Antibody (1A4)

• DBK
• EC 2.7.11
• MGC46204
• PAK1
• PAK1Serine-threonine protein kinase N
• PKN
• PKN1
• PKN-ALPHA
• PKNPKN-ALPHA
• PRK1
• PRK1PAK-1
• PRKCL1
• PRKCL1protein kinase C-related kinase 1
• Protease-activated kinase 1
• Protein kinase C-like 1EC 2.7.11.13
• Protein kinase C-like PKN
• protein kinase N1
• Protein kinase PKN-alpha
• Protein-kinase C-related kinase 1
• serine/threonine protein kinase N
• serine/threonine-protein kinase N1
• serine-threonine kinase N

Background

The protein encoded by this gene belongs to the protein kinase C superfamily. This kinase is activated by Rho family of small G proteins and may mediate the Rho-dependent signaling pathway. This kinase can be activated by phospholipids and by limited proteolysis. The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase, which may mediate insulin signals to the actin cytoskeleton. The proteolytic activation of this kinase by caspase-3 or related proteases during apoptosis suggests its role in signal transduction related to apoptosis. Alternatively spliced transcript variants encoding distinct isoforms have been observed. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PKN1
• Entrez:
  • 5585(Human)
• Uniprot:
  • AAH40061(Human)