PIEZO1 Antibody (CL9714) - Azide and BSA Free

Analysis in human lung and skeletal muscle tissues using NBP3-44234 antibody. Corresponding PIEZO1 RNA-seq data are presented for the same tissues.

Staining of human prostate shows moderate membranous positivity in glandular cells.

Staining of human lung shows moderate membranous positivity in pneumocytes.

Staining of human skeletal muscle shows no positivity in myocytes as expected.

Staining of human placenta shows moderate membranous positivity in endothelial cells.

Analysis in human cell line MCF-7.

• Reactivity: Hu
• Applications: WB, IHC
• Clone: CL9714
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

PIEZO1 Antibody (CL9714) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse PIEZO1 Antibody (CL9714) - Azide and BSA Free (NBP2-88938) is a monoclonal antibody validated for use in IHC and WB. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was generated using a synthetic peptide of Q92508, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PIEZO1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 1 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS with Trehalose
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A purified
• Reconstitution Instructions: Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Alternate Names for PIEZO1 Antibody (CL9714) - Azide and BSA Free

• FAM38A
• KIAA0233
• member A
• membrane protein induced by beta-amyloid treatment
• Mib
• PIEZO1
• piezo-type mechanosensitive ion channel component 1
• Protein FAM38A

Background

PIEZO1 (piezo-type mechanosensitive ion channel component 1) plays a crucial role in epithelial cell adhesion. PIEZO1 belongs to the PIEZO family of transmembrane proteins. Mutations in Piezo1 have been tied to Xerocytosis. PIEZO1 has been studied in relation to neuronitis, Alzheimer's disease and Parkinson's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PIEZO1