PIAS1 Antibody

Western Blot: PIAS1 Antibody [H00008554-B01P] - Analysis of PIAS1 expression in transfected 293T cell line by PIAS1 polyclonal antibody. Lane 1: PIAS1 transfected lysate(71.61 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

PIAS1 Antibody Summary

• Description: Quality control test: Antibody reactive against mammalian transfected lysate.
• Immunogen: PIAS1 (NP_057250.1, 1 a.a. - 651 a.a.) full-length human protein. MADSAELKQMVMSLRVSELQVLLGYAGRNKHGRKHELLTKALHLLKAGCSPAVQMKIKELYRRRFPQKIMTPADLSIPNVHSSPMPATLSPSTIPQLTYDGHPASSPLLPVSLLGPKHELELPHLTSALHPVHPDIKLQKLPFYDLLDELIKPTSLASDNSQRFRETCFAFALTPQQVQQISSSMDISGTKCDFTVQVQLRFCLSETSCPQEDHFPPNLCVKVNTKPCSLPGYLPPTKNGVEPKRPSRPINITSLVRLSTTVPNTIVVSWTAEIGRNYSMAVYLVKQLSSTVLLQRLRAKGIRNPDHSRALIKEKLTADPDSEIATTSLRVSLLCPLGKMRLTIPCRALTCSHLQCFDATLYIQMNEKKPTWVCPVCDKKAPYEHLIIDGLFMEILKYCTDCDEIQFKEDGTWAPMRSKKEVQEVSASYNGVDGCLSSTLEHQVASHHQSSNKNKKVEVIDLTIDSSSDEEEEEPSAKRTCPSLSPTSPLNNKGILSLPHQASPVSRTPSLPAVDTSYINTSLIQDYRHPFHMTPMPYDLQGLDFFPFLSGDNQHYNTSLLAAAAAAVSDDQDLLHSSRFFPYTSSQMFLDQLSAGGSTSLPTTNGSSSGSNSSLVSSNSLRESHSHTVTNRSSTDTASIFGIIPDIISLD
• Specificity: PIAS1 - protein inhibitor of activated STAT, 1,
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: PIAS1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB and also on transfected lysate in WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for PIAS1 Antibody

• AR interacting protein
• DDXBP1
• DDXBP1MGC141878
• DEAD/H (Asp-Glu-Ala-Asp/His) box binding protein 1
• DEAD/H box-binding protein 1
• E3 SUMO-protein ligase PIAS1
• GBPRNA helicase II-binding protein
• GU/RH-II
• Gu-binding protein
• MGC141879
• PIAS1
• Protein inhibitor of activated STAT protein 1
• protein inhibitor of activated STAT, 1
• protein inhibitor of activated STAT-1
• zinc finger, MIZ-type containing 3
• ZMIZ3

Background

This gene encodes a member of the mammalian PIAS [protein inhibitor of activated STAT-1 (signal transducer and activator of transcription-1)] family. This member contains a putative zinc-binding motif and a highly acidic region. It inhibits STAT1-mediated gene activation and the DNA binding activity, binds to Gu protein/RNA helicase II/DEAD box polypeptide 21, and interacts with androgen receptor (AR). It functions in testis as a nuclear receptor transcriptional coregulator and may have a role in AR initiation and maintenance of spermatogenesis. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PIAS1
• Entrez:
  • 8554(Human)
• Uniprot:
  • NP_057250.1(Human)