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PHOX2B Antibody

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Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications PEP-ELISA
Clonality
Polyclonal
Host
Goat
Conjugate
Unconjugated
Concentration
0.5 mg/ml

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PHOX2B Antibody Summary

Immunogen
Peptide with sequence C-SRDDESKEAKSTDP corresponding to internal region according to NP_003915.2.
Epitope
C terminus
Isotype
IgG
Clonality
Polyclonal
Host
Goat
Gene
PHOX2B
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Peptide ELISA Detection limit 1:1000
Application Notes
WB: Preliminary experiments in human brain (cerebellum) lysates gave no specific signal but low background.
Publications
Read Publication using NBP1-28488.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
Preservative
0.02% Sodium Azide
Concentration
0.5 mg/ml
Purity
Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for PHOX2B Antibody

  • NBPhox
  • NBPhoxPhox2b
  • Neuroblastoma Phox
  • paired mesoderm homeobox 2b
  • paired mesoderm homeobox protein 2B
  • paired-like homeobox 2bNBLST2
  • PHOX2B homeodomain protein
  • PHOX2B
  • PMX2B
  • PMX2Bneuroblastoma paired-type homeobox protein

Background

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol PHOX2B
Entrez
Uniprot