PHOX2B Antibody (PHOX2B/7161R) [Alexa Fluor™ Plus 488]

• Reactivity: Hu
• Applications: IHC
• Clone: PHOX2B/7161R
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 488

PHOX2B Antibody (PHOX2B/7161R) [Alexa Fluor™ Plus 488] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: Recombinant fragment of human PHOX2B protein (exact sequence is proprietary)
• Localization: Nucleus.
• Isotype: IgG Kappa
• Clonality: Monoclonal
• Host: Rabbit
• Gene: PHOX2B
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PHOX2B Antibody (PHOX2B/7161R) [Alexa Fluor™ Plus 488]

• NBPhox
• NBPhoxPhox2b
• Neuroblastoma Phox
• paired mesoderm homeobox 2b
• paired mesoderm homeobox protein 2B
• paired-like homeobox 2bNBLST2
• PHOX2B homeodomain protein
• PHOX2B
• PMX2B
• PMX2Bneuroblastoma paired-type homeobox protein

Background

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription factor involved in the development of several major noradrenergic neuron populations and the determination of neurotransmitter phenotype. The gene product is linked to enhancement of second messenger-mediated activation of the dopamine beta-hydroylase, c-fos promoters and several enhancers, including cyclic amp-response element and serum-response element. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PHOX2B