PHIP Antibody [HRP]

Product Discontinued

PHIP Antibody [HRP] Summary

• Immunogen: pleckstrin homology domain interacting protein. (Uniprot# Q8WWQ0)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PHIP
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: No Preservative
• Purity: Immunogen affinity purified

Alternate Names for PHIP Antibody [HRP]

• DCAF14
• DDB1 and CUL4 associated factor 14
• FLJ20705
• FLJ45918
• IRS-1 PH domain-binding protein
• MGC90216
• ndrp
• PH-interacting protein
• pleckstrin homology domain interacting protein
• WD repeat-containing protein 11
• WDR11

Background

PH-interacting protein (PHIP) was isolated as factor that binds to the pleckstrin homology (PH) domain of insulin receptor substrate-1 (IRS-1). PHIP was determined not to be a substrate of the insulin receptor but may instead serve to link IRS-1 to the insulin receptor. PHIP has also been implicated as a positive regulator of beta-cell mitogenesis and survival. PHIP is also known as WD-repeat-containing protein 11, WDR11, and IRS-1 PH domain-binding protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PHIP