PFKL Antibody

Immunohistochemistry-Paraffin: PFKL Antibody [NBP1-85934] - Staining of human liver shows moderate cytoplasmic positivity in hepatocytes.

Product Discontinued

PFKL Antibody Summary

• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: HGHTVYVVHDGFEGLAKGQVQEVGWHDVAGWLGRGGSMLGTKRTLPKGQLESIVENIRIYGIHALLVVGGFEAYEGVLQLVEARGRYEELCIVMCVIPATISNNVPGT
• Predicted Species: Mouse (92%), Rat (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PFKL
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for PFKL Antibody

• 6-phosphofructokinase, liver type
• DKFZp686G1648
• DKFZp686L2097
• EC 2.7.1
• EC 2.7.1.11
• FLJ30173
• FLJ40909
• human liver-type 1-phosphofructokinase, EC 2.7.1.1110Phosphohexokinase
• liver-type 1-phosphofructokinase
• PFK-B
• Phosphofructo-1-kinase isozyme B
• Phosphofructokinase 1
• phosphofructokinase, liver
• phosphohexokinase

Background

Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. Separate genes encode a muscle subunit (M) and a liver subunit (L). PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. The protein encoded by this gene represents the L subunit. Alternate splicing results in two transcript variants, one of which is a candidate for nonsense-mediated decay (NMD). [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PFKL