Species: Hu, Mu
Applications: WB
Host: Rabbit Polyclonal
Species: Hu, Pm-Or
Applications: WB, IP
Host: Rabbit Polyclonal
Species: Hu, Mu, Rt
Applications: WB
Host: Rabbit Monoclonal
Species: Hu
Applications: WB
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, PAGE, AP
Description
Phosphofructokinase (PFK) is a tetrameric enzyme that catalyzes a key step in glycolysis, namely the conversion of D-fructose 6-phosphate to D-fructose 1,6-bisphosphate. Separate genes encode a muscle subunit (M) and a liver subunit (L). PFK from muscle is a homotetramer of M subunits, PFK from liver is a homotetramer of L-subunits, while PFK from platelets can be composed of any tetrameric combination of M and L subunits. The protein encoded by this gene represents the L subunit. Alternate splicing results in two transcript variants, one of which is a candidate for nonsense-mediated decay (NMD). [provided by RefSeq]
Bioinformatics
| Uniprot |
Human Human Human Human |
| Product By Gene ID |
5211 |
| Alternate Names |
- 6-phosphofructokinase, liver type
- DKFZp686G1648
- DKFZp686L2097
- EC 2.7.1
- EC 2.7.1.11
- FLJ30173
- FLJ40909
- human liver-type 1-phosphofructokinase, EC 2.7.1.1110Phosphohexokinase
- liver-type 1-phosphofructokinase
- PFK-B
- Phosphofructo-1-kinase isozyme B
- Phosphofructokinase 1
- phosphofructokinase, liver
- phosphohexokinase
|
Research Areas for PFKL
Find related products by research area and learn more about each of the different research areas below.
Lipid and Metabolism